Latin America and the Caribbean (LAC) accounts for over a quarter of the world’s total cases, and a third of the total deaths, from the COVID-19 pandemic (1-4). In the absence of a vaccine to prevent the transmission of the virus, LAC countries have introduced several public health, health system, and economic policies to reduce the spread and impacts of COVID-19 (4,5). However, contextual factors such as fragmented health systems, limited social safety nets, and high levels of informal employment and inequality have further challenged the response to the pandemic in many of these countries (4,6,7). Furthermore, these underlying conditions intensify the impact of COVID-19, particularly for the most disadvantaged, including the unemployed, informal, and low-income workers, many of whom live in overcrowded households (4,7). In this study, we aim to describe policy interventions in 10 LAC countries in response to the COVID-19 pandemic, to compare these responses based on the experiences in two relatively high-performing jurisdictions, South Korea and Uruguay, and to support cross-jurisdictional policy learning for pandemic preparedness in the LAC region through knowledge exchange activities.

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